Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Color
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736
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750
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736
Tocris Bioscience™ Mefloquine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cx36 and Cx50 gap channel blocker
737
Tocris Bioscience™ MMG 11
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TLR2 antagonist
| Target | Toll-like Receptor Antagonists |
|---|---|
| CAS | 313254-94-3 |
| Purity | 97% |
| Chemical Name or Material | Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H14O7 |
738
Tocris Bioscience™ uPSEM 817 tartrate
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Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| CAS | 2341833-14-3 |
| Purity | 98% |
| Chemical Name or Material | 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H19N3O.C4H6O6 |
| Formula Weight | 419.43 |
739
Tocris Bioscience™ AZD 5363
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Potent pan-AKT inhibitor
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | Capivasertib |
| Molecular Formula | C21H25ClN6O2 |
| Formula Weight | 428.92 |
740
Tocris Bioscience™ Cyclosporin H
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Enhances lentiviral transduction
741
Tocris Bioscience™ PDD 00017238
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity and potent PARG inhibitor
742
Tocris Bioscience™ HMR 1556
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective Iks channel blocker
743
Tocris Bioscience™ MDL 72222
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 40796-97-2 Molecular Formula: C15H17Cl2NO2
| CAS | 40796-97-2 |
|---|---|
| Molecular Formula | C15H17Cl2NO2 |
744
Tocris Bioscience™ PJ 34 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 344458-15-7 Molecular Formula: C17H18ClN3O2
| CAS | 344458-15-7 |
|---|---|
| Molecular Formula | C17H18ClN3O2 |
745
Tocris Bioscience™ 4-CMTB
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 300851-67-6 Molecular Formula: C14H15ClN2OS
| CAS | 300851-67-6 |
|---|---|
| Molecular Formula | C14H15ClN2OS |
746
Tocris Bioscience™ Darunavir
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent HIV protease inhibitor
| Target | HIV Protease Inhibitors |
|---|---|
| CAS | 206361-99-1 |
| Purity | 98% |
| Chemical Name or Material | (3 R,3 AS,6 aR)-Hexahydrofuro[2,3-b]furan-3-yl N-[(1 S,2 R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H37N3O7S |
| Formula Weight | 547.66 |
747
Tocris Bioscience™ Decitabine
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CAS: 2353-33-5 Molecular Formula: C9H13N3O4
| CAS | 2353-33-5 |
|---|---|
| Molecular Formula | C9H13N3O4 |
748
Tocris Bioscience™ Pomalidomide 4'-alkylC5-azide
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
749
Tocris Bioscience™ OPC 21268
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CAS: 131631-89-5 Molecular Formula: C26H31N3O4
| CAS | 131631-89-5 |
|---|---|
| Molecular Formula | C26H31N3O4 |
750
Tocris Bioscience™ PHCCC
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CAS: 177610-87-6 Molecular Formula: C17H14N2O3
| CAS | 177610-87-6 |
|---|---|
| Molecular Formula | C17H14N2O3 |